(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol CAS 127852-28-2 Purity >99.0% (GC) Aprepitant Intermediate

Short Description:

(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol 

CAS: 127852-28-2

Purity: >99.0% (GC)  

Appearance: White to Off-White Powder

Intermediate of Aprepitant (CAS: 170729-80-3)

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Description:

Leading manufacturer and supplier
Intermediates of Aprepitant (CAS: 170729-80-3)
4-Benzyl-2-Hydroxymorpholin-3-one CAS 287930-73-8
(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol CAS 127852-28-2
Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol
Synonyms (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethyl Alcohol; (R)-3,5-Bis(trifluoromethyl)-α-Methylbenzyl Alcohol
CAS Number 127852-28-2
CAT Number RF-CC302
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C10H8F6O
Molecular Weight 258.16  
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance White to Off-White Powder
Purity / Analysis Method >99.0% (GC)  
Melting Point 53.0~57.0℃
Optical Rotation +26.0° ~ +29.0° (C=1 IN Acetonitrile)  
Infrared Spectrum Conforms to Structure
Test Standard Enterprise Standard
Usage Intermediate of Aprepitant (CAS: 170729-80-3)

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

1

FAQ:

Application:

(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol (CAS: 127852-28-2) is used as pharmaceutical intermediate, chiral synthesis for organic reactions, Aprepitant (CAS: 170729-80-3) intermediate. Aprepitant is an antiemetic chemical compound. Aprepitant is used for the prevention of acute and delayed chemotherapy-induced nausea and vomiting(CINV) and for prevention of postoperative nausea and vomiting. It was first successfully developed by Merck Company (German). In March 2003, the US Food and Drug Administration approved it for being used in the treatment of chemotherapy vomiting.

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